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The following keystrokes and commands provide various ways of sending code to a Guile client process for evaluation.

Evaluate the “top level defun” that the cursor is in, in other words the smallest balanced expression which includes the cursor and whose opening parenthesis is in column 0 (gds-eval-defun).
C-x C-e
Evaluate the expression that ends just before the cursor (gds-eval-last-sexp). This is designed so that it is easy to evaluate an expression that you have just finished typing.
C-c C-e
Read a Scheme expression using the minibuffer, and evaluate that expression (gds-eval-expression).
C-c C-r
Evaluate the Scheme code in the marked region of the current buffer (gds-eval-region). Note that GDS does not check whether the region contains a balanced expression, or try to expand the region so that it does; it uses the region exactly as it is.

If you type C-u before one of these commands, GDS will immediately pop up a Scheme stack buffer, showing the requested evaluation, so that you can single step through it. (This is achieved by setting a <source-trap> trap at the start of the requested evaluation; see Source Traps for more on how those work.) The Scheme stack display, and the options for continuing through the code, are described in the next two sections.